Currently, on the basis of electrophysiological studies in humans and in tissue culture conducting redundant system of the heart is customary to distinguish 4 cla*ses of antiarrhythmics.I belong to the cla*s of drugs that block the "fast" sodium channels, which leads to a decrease in the rate of depolarization, lengthening the duration of the action potential and refractory period, the suppression of automaticity.The duration of the blockade of sodium channels are divided into means of intermediate duration (from 2 to 5) - subcla*s Ia (quinidine, novokainamid, disopyramide), drugs subcla*s Ib (lidocaine, tokainid, Valium, phenytoin), providing short-term action (up to 1 s) and medications 1c subgroups have the most long-term (5) the effect on sodium channels (flecainide, enkainid, propafenoin).In Cla*s II includes beta-blockers.To belong to cla*s III drugs that delay repolarization (amiodarone, bretily, sotalol).Cla*s IV include calcium channel blockers.
News: Samuel Kohan, PhD, Psychoanalyst Video
